General Structure Information
| PDB ID | 4iqy |
| HGNC Gene Label(s) | MACROD2 |
| Structure Name | crystal structure of the human protein-proximal adp-ribosyl-hydrolase macrod2 |
| Resolution | 1.55Å |
| Reference | AUTH G.JANKEVICIUS,M.HASSLER,B.GOLIA,V.RYBIN,M.ZACHARIAS,AUTH 2 G.TIMINSZKY,A.G.LADURNERTITL A FAMILY OF MACRODOMAIN PROTEINS REVERSES CELLULARTITL 2 MONO-ADP-RIBOSYLATION.REF NAT.STRUCT.MOL.BIOL. V. 20 508 2013REFN ISSN 1545-9993PMID 23474712DOI 10.1038/NSMB.2523 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 221 |
| Number Of SNVs | 48 |
| Number Of Permutations | 25315 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.225 |
| p-value | 0.002 |
COSMIC
| Number Of Residues | 221 |
| Number Of SNVs | 6 |
| Number Of Permutations | 4345 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.333 |
| p-value | 0.153 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.197 |
| p-value | 0.421 |