General Structure Information
| PDB ID | 4hab |
| HGNC Gene Label(s) | PLK1 |
| Structure Name | crystal structure of plk1 polo-box domain in complex with pl-49 |
| Resolution | 2.65Å |
| Reference | AUTH R.N.MURUGAN,J.E.PARK,D.LIM,M.AHN,C.CHEONG,T.KWON,K.Y.NAM,AUTH 2 S.H.CHOI,B.Y.KIM,D.Y.YOON,M.B.YAFFE,D.Y.YU,K.S.LEE,J.K.BANGTITL DEVELOPMENT OF CYCLIC PEPTOMER INHIBITORS TARGETING THETITL 2 POLO-BOX DOMAIN OF POLO-LIKE KINASE 1.REF BIOORG.MED.CHEM. V. 21 2623 2013REFN ISSN 0968-0896PMID 23498919DOI 10.1016/J.BMC.2013.02.020 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 223 |
| Number Of SNVs | 48 |
| Number Of Permutations | 8346 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.962 |