General Structure Information
| PDB ID | 4h27 |
| HGNC Gene Label(s) | SDS |
| Structure Name | modulating the function of human serine racemase and human serine dehydratase by protein engineering |
| Resolution | 1.3Å |
| Reference | AUTH C.Y.WANG,S.C.KU,C.C.LEE,A.H.WANGTITL MODULATING THE FUNCTION OF HUMAN SERINE RACEMASE AND HUMANTITL 2 SERINE DEHYDRATASE BY PROTEIN ENGINEERING.REF PROTEIN ENG.DES.SEL. V. 25 741 2012REFN ISSN 1741-0126PMID 23112234DOI 10.1093/PROTEIN/GZS078 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 317 |
| Number Of SNVs | 84 |
| Number Of Permutations | 11111 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.09 |
| p-value | 0.236 |
COSMIC
| Number Of Residues | 317 |
| Number Of SNVs | 4 |
| Number Of Permutations | 273 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.167 |
| p-value | 0.832 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.223 |
| p-value | 0.735 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
