General Structure Information
| PDB ID | 4gmj |
| HGNC Gene Label(s) | CNOT1 |
| Structure Name | structure of human not1 mif4g domain co-crystallized with caf1 |
| Resolution | 2.7Å |
| Reference | AUTH A.P.PETIT,L.WOHLBOLD,P.BAWANKAR,E.HUNTZINGER,S.SCHMIDT,AUTH 2 E.IZAURRALDE,O.WEICHENRIEDERTITL THE STRUCTURAL BASIS FOR THE INTERACTION BETWEEN THE CAF1TITL 2 NUCLEASE AND THE NOT1 SCAFFOLD OF THE HUMAN CCR4-NOTTITL 3 DEADENYLASE COMPLEXREF NUCLEIC ACIDS RES. V. 40 11058 2012REFN ISSN 0305-1048PMID 22977175DOI 10.1093/NAR/GKS883 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 225 |
| Number Of SNVs | 23 |
| Number Of Permutations | 11805 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.055 |
| p-value | 0.036 |
COSMIC
| Number Of Residues | 225 |
| Number Of SNVs | 4 |
| Number Of Permutations | 289 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.687 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.151 |
| p-value | 0.737 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
