General Structure Information
| PDB ID | 4gfv |
| HGNC Gene Label(s) | PTPN18 |
| Structure Name | ptpn18 in complex with her2-py1196 phosphor-peptides |
| Resolution | 2.1Å |
| Reference | AUTH H.M.WANG,F.YANG,Y.J.DU,D.X.YANG,Y.ZHANG,X.YU,J.P.SUNTITL PTPN18-HER2 PEPTIDESREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 286 |
| Number Of SNVs | 84 |
| Number Of Permutations | 40236 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.355 |
| p-value | 0.173 |
COSMIC
| Number Of Residues | 286 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.515 |
| p-value | 0.512 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
