General Structure Information
| PDB ID | 4g6l |
| HGNC Gene Label(s) | CCNC |
| Structure Name | crystal structure of human cdk8/cycc in the dmg-in conformation |
| Resolution | 2.7Å |
| Reference | AUTH E.V.SCHNEIDER,J.BOTTCHER,R.HUBER,K.MASKOS,L.NEUMANNTITL STRUCTURE-KINETIC RELATIONSHIP STUDY OF CDK8/CYCC SPECIFICTITL 2 COMPOUNDS.REF PROC.NATL.ACAD.SCI.USA V. 110 8081 2013REFN ISSN 0027-8424PMID 23630251DOI 10.1073/PNAS.1305378110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 264 |
| Number Of SNVs | 23 |
| Number Of Permutations | 14269 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.17 |
| p-value | 0.032 |