General Structure Information
| PDB ID | 4fv2 |
| HGNC Gene Label(s) | MAPK1 |
| Structure Name | crystal structure of the erk2 complexed with ek5 |
| Resolution | 2.0Å |
| Reference | AUTH Y.N.KANG,J.A.STUCKEY,X.XIETITL CRYSTAL STRUCTURE OF THE ERK2 COMPLEXED WITH EK5REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 344 |
| Number Of SNVs | 18 |
| Number Of Permutations | 2975 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.111 |
| p-value | 0.057 |
COSMIC
| Number Of Residues | 344 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1357 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.067 |
| p-value | 0.124 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 18 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.248 |
| p-value | 0.542 |