General Structure Information
| PDB ID | 4fr4 |
| HGNC Gene Label(s) | STK32A |
| Structure Name | crystal structure of human serine/threonine-protein kinase 32a (yank1) |
| Resolution | 2.29Å |
| Reference | AUTH A.CHAIKUAD,J.M.ELKINS,T.KROJER,P.MAHAJAN,S.GOUBIN,M.SZKLARZ,AUTH 2 A.TUMBER,J.WANG,P.SAVITSKY,B.SHRESTHA,N.DAGA,S.PICAUD,AUTH 3 O.FEDOROV,C.K.ALLERSTON,S.V.A.LATWIEL,M.VOLLMAR,P.CANNING,AUTH 4 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,S.KNAPP,AUTH 5 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASETITL 2 32A (YANK1)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 346 |
| Number Of SNVs | 90 |
| Number Of Permutations | 51288 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.016 |
| p-value | 0.639 |
COSMIC
| Number Of Residues | 346 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 90 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | 0.292 |
| p-value | 0.661 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
