General Structure Information
| PDB ID | 4fit |
| HGNC Gene Label(s) | FHIT |
| Structure Name | fhit-apo |
| Resolution | 2.5Å |
| Reference | AUTH C.D.LIMA,M.G.KLEIN,W.A.HENDRICKSONTITL STRUCTURE-BASED ANALYSIS OF CATALYSIS ANDTITL 2 SUBSTRATE DEFINITION IN THE HIT PROTEIN FAMILY.REF SCIENCE V. 278 286 1997REFN ISSN 0036-8075PMID 9323207DOI 10.1126/SCIENCE.278.5336.286 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 126 |
| Number Of SNVs | 49 |
| Number Of Permutations | 2860 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.11 |
| p-value | 0.213 |
COSMIC
| Number Of Residues | 126 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.697 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
