General Structure Information
| PDB ID | 4f7o |
| HGNC Gene Label(s) | COPS5 |
| Structure Name | crystal structure of csn5 |
| Resolution | 2.6Å |
| Reference | AUTH A.ECHALIER,Y.PAN,M.BIROL,N.TAVERNIER,L.PINTARD,F.HOH,C.EBEL,AUTH 2 N.GALOPHE,F.X.CLARET,C.DUMASTITL INSIGHTS INTO THE REGULATION OF THE HUMAN COP9 SIGNALOSOMETITL 2 CATALYTIC SUBUNIT, CSN5/JAB1.REF PROC.NATL.ACAD.SCI.USA V. 110 1273 2013REFN ISSN 0027-8424PMID 23288897DOI 10.1073/PNAS.1209345110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 225 |
| Number Of SNVs | 22 |
| Number Of Permutations | 9139 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.13 |
| p-value | 0.78 |
COSMIC
| Number Of Residues | 225 |
| Number Of SNVs | 4 |
| Number Of Permutations | 546 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.667 |
| p-value | 0.488 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.286 |
| p-value | 0.903 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
