General Structure Information
| PDB ID | 4f3t |
| HGNC Gene Label(s) | AGO2 |
| Structure Name | human argonaute-2 – mir-20a complex |
| Resolution | 2.25Å |
| Reference | AUTH E.ELKAYAM,C.D.KUHN,A.TOCILJ,A.D.HAASE,E.M.GREENE,G.J.HANNON,AUTH 2 L.JOSHUA-TORTITL THE STRUCTURE OF HUMAN ARGONAUTE-2 IN COMPLEX WITH MIR-20A.REF CELL(CAMBRIDGE,MASS.) V. 150 100 2012REFN ISSN 0092-8674PMID 22682761DOI 10.1016/J.CELL.2012.05.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 801 |
| Number Of SNVs | 64 |
| Number Of Permutations | 50557 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.037 |
| p-value | 0.891 |
COSMIC
| Number Of Residues | 801 |
| Number Of SNVs | 10 |
| Number Of Permutations | 11972 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.022 |
| p-value | 0.605 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.073 |
| p-value | 0.584 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
