General Structure Information
| PDB ID | 4eyj |
| HGNC Gene Label(s) | MAPK13 |
| Structure Name | mapk13 complex with inhibitor |
| Resolution | 2.1Å |
| Reference | AUTH Y.G.ALEVY,A.C.PATEL,A.G.ROMERO,D.A.PATEL,J.TUCKER,AUTH 2 W.T.ROSWIT,C.A.MILLER,R.F.HEIER,D.E.BYERS,T.J.BRETT,AUTH 3 M.J.HOLTZMANTITL IL-13-INDUCED AIRWAY MUCUS PRODUCTION IS ATTENUATED BYTITL 2 MAPK13 INHIBITION.REF J.CLIN.INVEST. V. 122 4555 2012REFN ISSN 0021-9738PMID 23187130DOI 10.1172/JCI64896 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 338 |
| Number Of SNVs | 99 |
| Number Of Permutations | 51804 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.152 |
| p-value | 0.454 |
COSMIC
| Number Of Residues | 338 |
| Number Of SNVs | 9 |
| Number Of Permutations | 4840 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.083 |
| p-value | 0.457 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 99 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.063 |
| p-value | 0.983 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
