General Structure Information
| PDB ID | 4ern |
| HGNC Gene Label(s) | ERCC3 |
| Structure Name | crystal structure of the c-terminal domain of human xpb/ercc-3 excision repair protein at 1.80 a |
| Resolution | 1.8Å |
| Reference | AUTH E.HILARIO,Y.LI,Y.NOBUMORI,X.LIU,L.FANTITL STRUCTURE OF THE C-TERMINAL HALF OF HUMAN XPB HELICASE ANDTITL 2 THE IMPACT OF THE DISEASE-CAUSING MUTATION XP11BE.REF ACTA CRYSTALLOGR.,SECT.D V. 69 237 2013REFN ISSN 0907-4449PMID 23385459DOI 10.1107/S0907444912045040 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 229 |
| Number Of SNVs | 50 |
| Number Of Permutations | 5192 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.114 |
| p-value | 0.011 |
COSMIC
| Number Of Residues | 229 |
| Number Of SNVs | 5 |
| Number Of Permutations | 70 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.3 |
| p-value | 0.361 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.403 |
| p-value | 0.26 |