General Structure Information
| PDB ID | 4egx |
| HGNC Gene Label(s) | KIF1A |
| Structure Name | crystal structure of kif1a cc1-fha tandem |
| Resolution | 2.51Å |
| Reference | AUTH L.HUO,Y.YUE,J.REN,J.YU,J.LIU,Y.YU,F.YE,T.XU,M.ZHANG,W.FENGTITL THE CC1-FHA TANDEM AS A CENTRAL HUB FOR CONTROLLING THETITL 2 DIMERIZATION AND ACTIVATION OF KINESIN-3 KIF1AREF STRUCTURE V. 20 1550 2012REFN ISSN 0969-2126PMID 22863567DOI 10.1016/J.STR.2012.07.002 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 176 |
| Number Of SNVs | 17 |
| Number Of Permutations | 17817 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.11 |
| p-value | 0.967 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.245 |
| p-value | 0.446 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
