General Structure Information
| PDB ID | 4eeg |
| HGNC Gene Label(s) | B4GALT1 |
| Structure Name | crystal structure of human m340h-beta-1,4-galactosyltransferase-1 (m340h-b4gal-t1) in complex with glcnac-beta1,6-gal-beta |
| Resolution | 2.2Å |
| Reference | AUTH B.RAMAKRISHNAN,E.BOEGGEMAN,P.K.QASBATITL BINDING OF N-ACETYLGLUCOSAMINE (GLCNAC) BETA 1-6-BRANCHEDTITL 2 OLIGOSACCHARIDE ACCEPTORS TO BETA 4-GALACTOSYLTRANSFERASE ITITL 3 REVEALS A NEW LIGAND BINDING MODE.REF J.BIOL.CHEM. V. 287 28666 2012REFN ISSN 0021-9258PMID 22740701DOI 10.1074/JBC.M112.373514 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 273 |
| Number Of SNVs | 65 |
| Number Of Permutations | 9417 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.013 |
| p-value | 0.498 |
COSMIC
| Number Of Residues | 273 |
| Number Of SNVs | 4 |
| Number Of Permutations | 423 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.613 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.133 |
| p-value | 0.649 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
