General Structure Information
| PDB ID | 4dm9 |
| HGNC Gene Label(s) | UCHL1 |
| Structure Name | the crystal structure of ubiquitin carboxy-terminal hydrolase l1 (uchl1) bound to a tripeptide fluoromethyl ketone z-vae(ome)-fmk |
| Resolution | 2.35Å |
| Reference | AUTH C.W.DAVIES,J.CHANEY,G.KORBEL,D.RINGE,G.A.PETSKO,H.PLOEGH,AUTH 2 C.DASTITL THE CO-CRYSTAL STRUCTURE OF UBIQUITIN CARBOXY-TERMINALTITL 2 HYDROLASE L1 (UCHL1) WITH A TRIPEPTIDE FLUOROMETHYL KETONETITL 3 (Z-VAE(OME)-FMK).REF BIOORG.MED.CHEM.LETT. V. 22 3900 2012REFN ISSN 0960-894XPMID 22617491DOI 10.1016/J.BMCL.2012.04.124 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 223 |
| Number Of SNVs | 46 |
| Number Of Permutations | 14536 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.023 |
| p-value | 0.75 |
COSMIC
| Number Of Residues | 223 |
| Number Of SNVs | 5 |
| Number Of Permutations | 74 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.1 |
| p-value | 0.336 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 46 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.379 |
| p-value | 0.06 |