General Structure Information
| PDB ID | 4dlj |
| HGNC Gene Label(s) | MAPK14 |
| Structure Name | human p38 map kinase in complex with rl163 |
| Resolution | 2.6Å |
| Reference | AUTH M.GETLIK,J.R.SIMARD,M.TERMATHE,C.GRUTTER,M.RABILLER,AUTH 2 W.A.VAN OTTERLO,D.RAUHTITL FLUOROPHORE LABELED KINASE DETECTS LIGANDS THAT BIND WITHINTITL 2 THE MAPK INSERT OF P38ALPHA KINASE.REF PLOS ONE V. 7 39713 2012REFN ESSN 1932-6203PMID 22768308DOI 10.1371/JOURNAL.PONE.0039713 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 336 |
| Number Of SNVs | 38 |
| Number Of Permutations | 7198 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.034 |
| p-value | 0.936 |
COSMIC
| Number Of Residues | 336 |
| Number Of SNVs | 4 |
| Number Of Permutations | 42 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.335 |
| p-value | 0.54 |