General Structure Information
| PDB ID | 4cnc |
| HGNC Gene Label(s) | TPBG |
| Structure Name | crystal structure of human 5t4 (wnt-activated inhibitory factor 1, trophoblast glycoprotein) |
| Resolution | 1.77Å |
| Reference | AUTH Y.ZHAO,T.MALINAUSKAS,K.HARLOS,E.Y.JONESTITL STRUCTURAL INSIGHTS INTO THE INHIBITION OF WNT SIGNALING BYTITL 2 CANCER ANTIGEN 5T4/WNT-ACTIVATED INHIBITORY FACTOR 1.REF STRUCTURE V. 22 612 2014REFN ISSN 0969-2126PMID 24582434DOI 10.1016/J.STR.2014.01.009 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 278 |
| Number Of SNVs | 82 |
| Number Of Permutations | 47140 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.179 |
| p-value | 0.026 |
COSMIC
| Number Of Residues | 278 |
| Number Of SNVs | 3 |
| Number Of Permutations | 407 |
| Optimal Distance Threshold | 50.0 |
| K Statistic | 0.667 |
| p-value | 0.378 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 82 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 36.0 |
| K Statistic | -0.411 |
| p-value | 0.039 |