General Structure Information
| PDB ID | 4ch9 |
| HGNC Gene Label(s) | KLHL3 |
| Structure Name | crystal structure of the human klhl3 kelch domain in complex with a wnk4 peptide |
| Resolution | 1.84Å |
| Reference | AUTH F.SCHUMACHER,F.J.SORRELL,D.R.ALESSI,A.N.BULLOCK,T.KURZTITL STRUCTURAL AND BIOCHEMICAL CHARACTERISATION OF THE KLHL3-TITL 2 WNK KINASE INTERACTION IMPORTANT IN BLOOD PRESSURETITL 3 REGULATION.REF BIOCHEM.J. V. 460 237 2014REFN ISSN 0264-6021PMID 24641320DOI 10.1042/BJ20140153 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 286 |
| Number Of SNVs | 60 |
| Number Of Permutations | 18469 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.032 |
| p-value | 0.287 |
ClinVar
| Number Of Residues | 286 |
| Number Of SNVs | 18 |
| Number Of Permutations | 5513 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.32 |
| p-value | 0.001 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of ClinVar SNVs | 18 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.137 |
| p-value | 0.0 |