General Structure Information
| PDB ID | 4bcj |
| HGNC Gene Label(s) | CDK9 |
| Structure Name | structure of cdk9 in complex with cyclin t and a 2-amino-4- heteroaryl-pyrimidine inhibitor |
| Resolution | 3.16Å |
| Reference | AUTH A.J.HOLE,S.BAUMLI,H.SHAO,S.SHI,C.PEPPER,P.M.FISCHER,S.WANG,AUTH 2 J.A.ENDICOTT,M.E.M.NOBLETITL COMPARATIVE STRUCTURAL AND FUNCTIONAL STUDIES OFTITL 2 4-(THIAZOL- 5-YL)-2-(PHENYLAMINO)PYRIMIDINE-5-CARBONITRILETITL 3 CDK9 INHIBITORS SUGGEST THE BASIS FOR ISOTYPE SELECTIVITY.REF J.MED.CHEM. V. 56 660 2013REFN ISSN 0022-2623PMID 23252711DOI 10.1021/JM301495V |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 309 |
| Number Of SNVs | 57 |
| Number Of Permutations | 39211 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.019 |
| p-value | 0.801 |