General Structure Information
| PDB ID | 4b18 |
| HGNC Gene Label(s) | KPNA1 |
| Structure Name | the crystal structure of human importin alpha 5 with tert nls peptide |
| Resolution | 2.52Å |
| Reference | AUTH S.A.JEONG,K.KIM,J.H.LEE,J.S.CHA,P.KHADKA,H.CHO,I.K.CHUNGTITL AKT-MEDIATED PHOSPHORYLATION INCREASES THE BINDING AFFINITYTITL 2 OF HTERT FOR IMPORTIN ALPHA TO PROMOTE NUCLEARTITL 3 TRANSLOCATION.REF J.CELL.SCI. V. 128 2287 2015REFN ISSN 0021-9533PMID 25999477DOI 10.1242/JCS.166132 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 427 |
| Number Of SNVs | 57 |
| Number Of Permutations | 52257 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.376 |
| p-value | 0.125 |
COSMIC
| Number Of Residues | 427 |
| Number Of SNVs | 4 |
| Number Of Permutations | 41 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 0.435 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
