4A1G.A | BUB1

General Structure Information

PDB ID 4a1g
HGNC Gene Label(s) BUB1
Structure Name the crystal structure of the human bub1 tpr domain in complex with the ki motif of knl1
Resolution 2.6Å
Reference AUTH V.KRENN,A.WEHENKEL,X.LI,S.SANTAGUIDA,A.MUSACCHIOTITL STRUCTURAL ANALYSIS REVEALS FEATURES OF THE SPINDLETITL 2 CHECKPOINT KINASE BUB1-KINETOCHORE SUBUNIT KNL1TITL 3 INTERACTION.REF J.CELL BIOL. V. 196 451 2012REFN ISSN 0021-9525PMID 22331848DOI 10.1083/JCB.201110013

Variant Set Distributions

ExAC Variants

Number Of Residues 146
Number Of SNVs 41
Number Of Permutations 16519
Optimal Distance Threshold 17.0
K Statistic 0.388
p-value 0.706

Mapped Variants

[+] ExAC Missense Variants