General Structure Information
| PDB ID | 3zni |
| HGNC Gene Label(s) | CBLB |
| Structure Name | structure of phosphotyr363-cbl-b – ubch5b-ub – zap-70 peptide complex |
| Resolution | 2.21Å |
| Reference | AUTH H.DOU,L.BUETOW,G.J.SIBBET,K.CAMERON,D.T.HUANGTITL ESSENTIALITY OF A NON-RING ELEMENT IN PRIMING DONORTITL 2 UBIQUITIN FOR CATALYSIS BY A MONOMERIC E3.REF NAT.STRUCT.MOL.BIOL. V. 20 982 2013REFN ISSN 1545-9993PMID 23851457DOI 10.1038/NSMB.2621 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 389 |
| Number Of SNVs | 66 |
| Number Of Permutations | 43851 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.254 |
| p-value | 0.269 |
COSMIC
| Number Of Residues | 389 |
| Number Of SNVs | 3 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 66 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.281 |
| p-value | 0.512 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
