General Structure Information
| PDB ID | 3zkj |
| HGNC Gene Label(s) | ASB9 |
| Structure Name | crystal structure of ankyrin repeat and socs box-containing protein 9 (asb9) in complex with elonginb and elonginc |
| Resolution | 2.58Å |
| Reference | AUTH J.R.C.MUNIZ,K.GUO,N.J.KERSHAW,V.AYINAMPUDI,F.VON DELFT,AUTH 2 J.J.BABON,A.N.BULLOCKTITL MOLECULAR ARCHITECTURE OF THE ANKYRIN SOCS BOX FAMILY OFTITL 2 CUL5-DEPENDENT E3 UBIQUITIN LIGASESREF J.MOL.BIOL. V. 425 3166 2013REFN ISSN 0022-2836PMID 23806657DOI 10.1016/J.JMB.2013.06.015 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 257 |
| Number Of SNVs | 45 |
| Number Of Permutations | 11903 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.054 |
| p-value | 0.896 |
COSMIC
| Number Of Residues | 257 |
| Number Of SNVs | 3 |
| Number Of Permutations | 76 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.667 |
| p-value | 0.082 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.541 |
| p-value | 0.089 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
