General Structure Information
| PDB ID | 3zjd |
| HGNC Gene Label(s) | TNFAIP3 |
| Structure Name | a20 otu domain in reduced, active state at 1.87 a resolution |
| Resolution | 1.87Å |
| Reference | AUTH Y.KULATHU,F.J.GARCIA,T.E.T.MEVISSEN,M.BUSCH,N.ARNAUDO,AUTH 2 K.S.CARROLL,D.BARFORD,D.KOMANDERTITL REGULATION OF A20 AND OTHER OTU DEUBIQUITINASES BYTITL 2 REVERSIBLE OXIDATIONREF NAT.COMMUN. V. 4 1569 2013REFN ISSN 2041-1723PMID 23463012DOI 10.1038/NCOMMS2567 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 325 |
| Number Of SNVs | 68 |
| Number Of Permutations | 12715 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.025 |
| p-value | 0.827 |
COSMIC
| Number Of Residues | 325 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1818 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.578 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.087 |
| p-value | 0.64 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
