General Structure Information
| PDB ID | 3zjc |
| HGNC Gene Label(s) | GIMAP7 |
| Structure Name | crystal structure of gmppnp-bound human gimap7 l100q variant |
| Resolution | 3.15Å |
| Reference | AUTH D.SCHWEFEL,B.S.ARASU,S.F.MARINO,B.LAMPRECHT,K.KOECHERT,AUTH 2 E.ROSENBAUM,J.EICHHORST,B.WIESNER,J.BEHLKE,O.ROCKS,S.MATHAS,AUTH 3 O.DAUMKETITL STRUCTURAL INSIGHTS INTO THE MECHANISM OF GTPASE ACTIVATIONTITL 2 IN THE GIMAP FAMILY.REF STRUCTURE V. 21 550 2013REFN ISSN 0969-2126PMID 23454188DOI 10.1016/J.STR.2013.01.014 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 257 |
| Number Of SNVs | 67 |
| Number Of Permutations | 40179 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.033 |
| p-value | 0.981 |
COSMIC
| Number Of Residues | 257 |
| Number Of SNVs | 7 |
| Number Of Permutations | 2566 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.238 |
| p-value | 0.094 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.172 |
| p-value | 0.3 |