General Structure Information
| PDB ID | 3zgo |
| HGNC Gene Label(s) | SIRT2 |
| Structure Name | re-refined structure of the human sirt2 apoform |
| Resolution | 1.63Å |
| Reference | AUTH S.MONIOT,M.SCHUTKOWSKI,C.STEEGBORNTITL CRYSTAL STRUCTURE ANALYSIS OF HUMAN SIRT2 AND ITSTITL 2 ADP-RIBOSE COMPLEXREF J.STRUCT.BIOL. V. 182 136 2013REFN ISSN 1047-8477PMID 23454361DOI 10.1016/J.JSB.2013.02.012 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 316 |
| Number Of SNVs | 89 |
| Number Of Permutations | 16607 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.011 |
| p-value | 0.115 |
COSMIC
| Number Of Residues | 316 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 89 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.513 |
| p-value | 0.263 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
