General Structure Information
| PDB ID | 3zfm |
| HGNC Gene Label(s) | EPHB2 |
| Structure Name | crystal structure of ephb2 |
| Resolution | 2.27Å |
| Reference | AUTH R.C.OVERMAN,J.E.DEBRECZENI,C.M.TRUMAN,M.S.MCALISTER,AUTH 2 T.K.ATTWOODTITL COMPLETING THE STRUCTURAL FAMILY PORTRAIT OF THE HUMAN EPHBTITL 2 TYROSINE KINASE DOMAINSREF PROTEIN SCI. V. 23 627 2014REFN ISSN 0961-8368PMID 24677421DOI 10.1002/PRO.2445 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 249 |
| Number Of SNVs | 61 |
| Number Of Permutations | 30838 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.177 |
| p-value | 0.527 |
COSMIC
| Number Of Residues | 249 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1334 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.5 |
| p-value | 0.791 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.125 |
| p-value | 0.475 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
