General Structure Information
| PDB ID | 3zd2 |
| HGNC Gene Label(s) | CFHR1 |
| Structure Name | the structure of the two n-terminal domains of complement factor h related protein 1 shows formation of a novel dimerisation interface |
| Resolution | 1.99Å |
| Reference | AUTH E.GOICOECHEA DE JORGE,J.J.E.CAESAR,T.H.MALIK,M.PATEL,AUTH 2 M.COLLEDGE,S.JOHNSON,S.HAKOBYAN,B.P.MORGAN,C.L.HARRIS,AUTH 3 M.C.PICKERING,S.M.LEATITL DIMERIZATION OF COMPLEMENT FACTOR H-RELATED PROTEINSTITL 2 MODULATES COMPLEMENT ACTIVATION IN VIVO.REF PROC.NATL.ACAD.SCI.USA V. 110 4685 2013REFN ISSN 0027-8424PMID 23487775DOI 10.1073/PNAS.1219260110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 125 |
| Number Of SNVs | 32 |
| Number Of Permutations | 6156 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.129 |
| p-value | 0.869 |