General Structure Information
| PDB ID | 3vwk |
| HGNC Gene Label(s) | CD1D |
| Structure Name | ternary crystal structure of the human nkt tcr-cd1d-4deoxy-alpha- galactosylceramide complex |
| Resolution | 2.94Å |
| Reference | AUTH K.S.WUN,F.ROSS,O.PATEL,G.S.BESRA,S.A.PORCELLI,AUTH 2 S.K.RICHARDSON,S.KESHIPEDDY,A.R.HOWELL,D.I.GODFREY,AUTH 3 J.ROSSJOHNTITL HUMAN AND MOUSE TYPE I NATURAL KILLER T CELL ANTIGENTITL 2 RECEPTORS EXHIBIT DIFFERENT FINE SPECIFICITIES FORTITL 3 CD1D-ANTIGEN COMPLEXREF J.BIOL.CHEM. V. 287 39139 2012REFN ISSN 0021-9258PMID 22995911DOI 10.1074/JBC.M112.412320 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 249 |
| Number Of SNVs | 74 |
| Number Of Permutations | 40608 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.042 |
| p-value | 0.336 |
COSMIC
| Number Of Residues | 249 |
| Number Of SNVs | 5 |
| Number Of Permutations | 423 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.2 |
| p-value | 0.52 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 74 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.378 |
| p-value | 0.297 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
