General Structure Information
| PDB ID | 3vw7 |
| HGNC Gene Label(s) | F2R |
| Structure Name | crystal structure of human protease-activated receptor 1 (par1) bound with antagonist vorapaxar at 2.2 angstrom |
| Resolution | 2.2Å |
| Reference | AUTH C.ZHANG,Y.SRINIVASAN,D.H.ARLOW,J.J.FUNG,D.PALMER,Y.ZHENG,AUTH 2 H.F.GREEN,A.PANDEY,R.O.DROR,D.E.SHAW,W.I.WEIS,S.R.COUGHLIN,AUTH 3 B.K.KOBILKATITL HIGH-RESOLUTION CRYSTAL STRUCTURE OF HUMANTITL 2 PROTEASE-ACTIVATED RECEPTOR 1REF NATURE V. 492 387 2012REFN ISSN 0028-0836PMID 23222541DOI 10.1038/NATURE11701 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 282 |
| Number Of SNVs | 71 |
| Number Of Permutations | 46636 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.408 |
| p-value | 0.399 |