General Structure Information
| PDB ID | 3urf |
| HGNC Gene Label(s) | TNFRSF11B |
| Structure Name | human rankl/opg complex |
| Resolution | 2.7Å |
| Reference | AUTH X.D.LUAN,Q.Y.LU,Y.N.JIANG,S.Y.ZHANG,Q.WANG,H.H.YUAN,AUTH 2 W.M.ZHAO,J.W.WANG,X.Q.WANGTITL CRYSTAL STRUCTURE OF HUMAN RANKL COMPLEXED WITH ITS DECOYTITL 2 RECEPTOR OSTEOPROTEGERINREF J.IMMUNOL. V. 189 245 2012REFN ISSN 0022-1767PMID 22664871DOI 10.4049/JIMMUNOL.1103387 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 161 |
| Number Of SNVs | 41 |
| Number Of Permutations | 12185 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.337 |
ClinVar
| Number Of Residues | 161 |
| Number Of SNVs | 4 |
| Number Of Permutations | 942 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 0.61 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.122 |
| p-value | 0.699 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
