General Structure Information
| PDB ID | 3urf |
| HGNC Gene Label(s) | TNFSF11 |
| Structure Name | human rankl/opg complex |
| Resolution | 2.7Å |
| Reference | AUTH X.D.LUAN,Q.Y.LU,Y.N.JIANG,S.Y.ZHANG,Q.WANG,H.H.YUAN,AUTH 2 W.M.ZHAO,J.W.WANG,X.Q.WANGTITL CRYSTAL STRUCTURE OF HUMAN RANKL COMPLEXED WITH ITS DECOYTITL 2 RECEPTOR OSTEOPROTEGERINREF J.IMMUNOL. V. 189 245 2012REFN ISSN 0022-1767PMID 22664871DOI 10.4049/JIMMUNOL.1103387 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 156 |
| Number Of SNVs | 35 |
| Number Of Permutations | 15952 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.151 |
| p-value | 0.493 |
COSMIC
| Number Of Residues | 156 |
| Number Of SNVs | 7 |
| Number Of Permutations | 510 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.095 |
| p-value | 0.802 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.319 |
| p-value | 0.19 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
