General Structure Information
| PDB ID | 3uoa |
| HGNC Gene Label(s) | MALT1 |
| Structure Name | crystal structure of the malt1 paracaspase (p21 form) |
| Resolution | 1.75Å |
| Reference | AUTH J.W.YU,P.D.JEFFREY,J.Y.HA,X.YANG,Y.SHITITL CRYSTAL STRUCTURE OF THE MUCOSA-ASSOCIATED LYMPHOID TISSUETITL 2 LYMPHOMA TRANSLOCATION 1 (MALT1) PARACASPASE REGION.REF PROC.NATL.ACAD.SCI.USA V. 108 21004 2011REFN ISSN 0027-8424PMID 22158899DOI 10.1073/PNAS.1111708108 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 55 |
| Number Of Permutations | 17033 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.388 |
| p-value | 0.251 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 4 |
| Number Of Permutations | 465 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.833 |
| p-value | 0.467 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 55 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.543 |
| p-value | 0.203 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
