General Structure Information
| PDB ID | 3ujr |
| HGNC Gene Label(s) | ENO2 |
| Structure Name | asymmetric complex of human neuron specific enolase-5-pga/pep |
| Resolution | 1.4Å |
| Reference | AUTH J.QIN,G.CHAI,J.M.BREWER,L.L.LOVELACE,L.LEBIODATITL STRUCTURES OF ASYMMETRIC COMPLEXES OF HUMAN NEURON SPECIFICTITL 2 ENOLASE WITH RESOLVED SUBSTRATE AND PRODUCT AND AN ANALOGOUSTITL 3 COMPLEX WITH TWO INHIBITORS INDICATE SUBUNIT INTERACTION ANDTITL 4 INHIBITOR COOPERATIVITY.REF J.INORG.BIOCHEM. V. 111 187 2012REFN ISSN 0162-0134PMID 22437160DOI 10.1016/J.JINORGBIO.2012.02.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 433 |
| Number Of SNVs | 87 |
| Number Of Permutations | 14279 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.817 |
COSMIC
| Number Of Residues | 433 |
| Number Of SNVs | 5 |
| Number Of Permutations | 651 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.2 |
| p-value | 0.546 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.201 |
| p-value | 0.258 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
