General Structure Information
| PDB ID | 3uiu |
| HGNC Gene Label(s) | EIF2AK2 |
| Structure Name | crystal structure of apo-pkr kinase domain |
| Resolution | 2.9Å |
| Reference | AUTH F.LI,S.LI,X.YANG,Y.SHEN,T.ZHANGTITL CRYSTAL STRUCTURE OF APO-PKR KINASE DOMAINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 255 |
| Number Of SNVs | 42 |
| Number Of Permutations | 7719 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.271 |
| p-value | 0.01 |
COSMIC
| Number Of Residues | 255 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.366 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
