General Structure Information
| PDB ID | 3u8z |
| HGNC Gene Label(s) | NF2 |
| Structure Name | human merlin ferm domain |
| Resolution | 2.64Å |
| Reference | AUTH S.D.YOGESHA,A.J.SHARFF,M.GIOVANNINI,G.BRICOGNE,T.IZARDTITL UNFURLING OF THE BAND 4.1, EZRIN, RADIXIN, MOESIN (FERM)TITL 2 DOMAIN OF THE MERLIN TUMOR SUPPRESSOR.REF PROTEIN SCI. V. 20 2113 2011REFN ISSN 0961-8368PMID 22012890DOI 10.1002/PRO.751 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 266 |
| Number Of SNVs | 36 |
| Number Of Permutations | 32054 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.033 |
| p-value | 0.599 |
COSMIC
| Number Of Residues | 266 |
| Number Of SNVs | 10 |
| Number Of Permutations | 3284 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.022 |
| p-value | 0.825 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.213 |
| p-value | 0.36 |