3TWR.B | TNKS2

General Structure Information

PDB ID 3twr
HGNC Gene Label(s) TNKS2
Structure Name crystal structure of arc4 from human tankyrase 2 in complex with peptide from human 3bp2
Resolution 1.55Å
Reference AUTH S.GUETTLER,J.LAROSE,E.PETSALAKI,G.GISH,A.SCOTTER,T.PAWSON,AUTH 2 R.ROTTAPEL,F.SICHERITITL STRUCTURAL BASIS AND SEQUENCE RULES FOR SUBSTRATETITL 2 RECOGNITION BY TANKYRASE EXPLAIN THE BASIS FOR CHERUBISMTITL 3 DISEASE.REF CELL(CAMBRIDGE,MASS.) V. 147 1340 2011REFN ISSN 0092-8674PMID 22153077DOI 10.1016/J.CELL.2011.10.046

Variant Set Distributions

ExAC Variants

Number Of Residues 157
Number Of SNVs 21
Number Of Permutations 2595
Optimal Distance Threshold 10.0
K Statistic 0.105
p-value 0.897

Mapped Variants

[+] ExAC Missense Variants