General Structure Information
| PDB ID | 3tk9 |
| HGNC Gene Label(s) | GZMH |
| Structure Name | crystal structure of human granzyme h |
| Resolution | 2.2Å |
| Reference | AUTH L.WANG,K.ZHANG,L.WU,S.LIU,H.ZHANG,Q.ZHOU,L.TONG,F.SUN,Z.FANTITL STRUCTURAL INSIGHTS INTO THE SUBSTRATE SPECIFICITY OF HUMANTITL 2 GRANZYME H: THE FUNCTIONAL ROLES OF A NOVEL RKR MOTIFREF J.IMMUNOL. V. 188 765 2012REFN ISSN 0022-1767PMID 22156497DOI 10.4049/JIMMUNOL.1101381 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 226 |
| Number Of SNVs | 61 |
| Number Of Permutations | 19737 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.297 |
| p-value | 0.025 |
COSMIC
| Number Of Residues | 226 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.37 |
| p-value | 0.561 |