General Structure Information
| PDB ID | 3th7 |
| HGNC Gene Label(s) | ARG1 |
| Structure Name | crystal structure of unliganded co2+2-hai (ph 7.0) |
| Resolution | 2.1Å |
| Reference | AUTH E.L.DANTONIO,D.W.CHRISTIANSONTITL CRYSTAL STRUCTURES OF COMPLEXES WITH COBALT-RECONSTITUTEDTITL 2 HUMAN ARGINASE I.REF BIOCHEMISTRY V. 50 8018 2011REFN ISSN 0006-2960PMID 21870783DOI 10.1021/BI201101T |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 314 |
| Number Of SNVs | 76 |
| Number Of Permutations | 19263 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.021 |
| p-value | 0.693 |
ClinVar
| Number Of Residues | 314 |
| Number Of SNVs | 4 |
| Number Of Permutations | 536 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.0 |
| p-value | 0.31 |
COSMIC
| Number Of Residues | 314 |
| Number Of SNVs | 4 |
| Number Of Permutations | 316 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.5 |
| p-value | 0.015 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.248 |
| p-value | 0.323 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.467 |
| p-value | 0.373 |