General Structure Information
| PDB ID | 3soa |
| HGNC Gene Label(s) | CAMK2A |
| Structure Name | full-length human camkii |
| Resolution | 3.55Å |
| Reference | AUTH L.H.CHAO,M.M.STRATTON,I.H.LEE,O.S.ROSENBERG,J.LEVITZ,AUTH 2 D.J.MANDELL,T.KORTEMME,J.T.GROVES,H.SCHULMAN,J.KURIYANTITL A MECHANISM FOR TUNABLE AUTOINHIBITION IN THE STRUCTURE OF ATITL 2 HUMAN CA(2+)/CALMODULIN- DEPENDENT KINASE II HOLOENZYME.REF CELL(CAMBRIDGE,MASS.) V. 146 732 2011REFN ISSN 0092-8674PMID 21884935DOI 10.1016/J.CELL.2011.07.038 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 436 |
| Number Of SNVs | 34 |
| Number Of Permutations | 6617 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.05 |
| p-value | 0.234 |
COSMIC
| Number Of Residues | 436 |
| Number Of SNVs | 8 |
| Number Of Permutations | 2013 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.071 |
| p-value | 0.181 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.124 |
| p-value | 0.876 |