General Structure Information
| PDB ID | 3snh |
| HGNC Gene Label(s) | DNM1 |
| Structure Name | crystal structure of nucleotide-free human dynamin1 |
| Resolution | 3.7Å |
| Reference | AUTH K.FAELBER,Y.POSOR,S.GAO,M.HELD,Y.ROSKE,D.SCHULZE,V.HAUCKE,AUTH 2 F.NOE,O.DAUMKETITL CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE DYNAMIN.REF NATURE V. 477 556 2011REFN ISSN 0028-0836PMID 21927000DOI 10.1038/NATURE10369 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 652 |
| Number Of SNVs | 77 |
| Number Of Permutations | 33450 |
| Optimal Distance Threshold | 44.0 |
| K Statistic | 0.5 |
| p-value | 0.465 |
ClinVar
| Number Of Residues | 652 |
| Number Of SNVs | 3 |
| Number Of Permutations | 591 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.358 |
COSMIC
| Number Of Residues | 652 |
| Number Of SNVs | 9 |
| Number Of Permutations | 13394 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.389 |
| p-value | 0.432 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.326 |
| p-value | 0.351 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.35 |
| p-value | 0.136 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
