General Structure Information
| PDB ID | 3rk2 |
| HGNC Gene Label(s) | SNAP25 |
| Structure Name | truncated snare complex |
| Resolution | 2.2Å |
| Reference | AUTH D.KUMMEL,S.S.KRISHNAKUMAR,D.T.RADOFF,F.LI,C.G.GIRAUDO,AUTH 2 F.PINCET,J.E.ROTHMAN,K.M.REINISCHTITL COMPLEXIN CROSS-LINKS PREFUSION SNARES INTO A ZIGZAG ARRAY.REF NAT.STRUCT.MOL.BIOL. V. 18 927 2011REFN ISSN 1545-9993PMID 21785414DOI 10.1038/NSMB.2101 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 63 |
| Number Of SNVs | 5 |
| Number Of Permutations | 3554 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.2 |
| p-value | 0.271 |
COSMIC
| Number Of Residues | 63 |
| Number Of SNVs | 4 |
| Number Of Permutations | 474 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.5 |
| p-value | 0.787 |
Ripley’s K Analysis Plots
COSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 5 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | -0.2 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
