General Structure Information
| PDB ID | 3rgh |
| HGNC Gene Label(s) | FLNA |
| Structure Name | structure of filamin a immunoglobulin-like repeat 10 from homo sapiens |
| Resolution | 2.44Å |
| Reference | AUTH R.C.PAGE,J.G.CLARK,S.MISRATITL STRUCTURE OF FILAMIN A IMMUNOGLOBULIN-LIKE REPEAT 10 FROMTITL 2 HOMO SAPIENS.REF ACTA CRYSTALLOGR.,SECT.F V. 67 871 2011REFN ESSN 1744-3091PMID 21821884DOI 10.1107/S1744309111024249 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 94 |
| Number Of SNVs | 13 |
| Number Of Permutations | 903 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.141 |
| p-value | 0.417 |
ClinVar
| Number Of Residues | 94 |
| Number Of SNVs | 5 |
| Number Of Permutations | 258 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.3 |
| p-value | 0.031 |
COSMIC
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 13 |
| Number Of ClinVar SNVs | 5 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.21 |
| p-value | 0.156 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 13 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.244 |
| p-value | 0.562 |