General Structure Information
| PDB ID | 3qd6 |
| HGNC Gene Label(s) | CD40LG |
| Structure Name | crystal structure of the cd40 and cd154 (cd40l) complex |
| Resolution | 3.5Å |
| Reference | AUTH H.-J.AN,Y.J.KIM,D.H.SONG,B.S.PARK,H.M.KIM,J.D.LEE,S.-G.PAIK,AUTH 2 J.-O.LEE,H.LEETITL CRYSTALLOGRAPHIC AND MUTATIONAL ANALYSIS OF THE CD40-CD154TITL 2 COMPLEX AND ITS IMPLICATIONS FOR RECEPTOR ACTIVATIONREF J.BIOL.CHEM. V. 286 11226 2011REFN ISSN 0021-9258PMID 21285457DOI 10.1074/JBC.M110.208215 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 135 |
| Number Of SNVs | 17 |
| Number Of Permutations | 6342 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.199 |
| p-value | 0.05 |
ClinVar
| Number Of Residues | 135 |
| Number Of SNVs | 9 |
| Number Of Permutations | 3376 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.278 |
| p-value | 0.063 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of ClinVar SNVs | 9 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.229 |
| p-value | 0.035 |