3PHD.G | UBA52

General Structure Information

PDB ID 3phd
HGNC Gene Label(s) UBA52
Structure Name crystal structure of human hdac6 in complex with ubiquitin
Resolution 3.0Å
Reference AUTH H.OUYANG,Y.O.ALI,M.RAVICHANDRAN,A.DONG,W.QIU,F.MACKENZIE,AUTH 2 S.DHE-PAGANON,C.H.ARROWSMITH,R.G.ZHAITITL PROTEIN AGGREGATES ARE RECRUITED TO AGGRESOME BY HISTONETITL 2 DEACETYLASE 6 VIA UNANCHORED UBIQUITIN C TERMINI.REF J.BIOL.CHEM. V. 287 2317 2012REFN ISSN 0021-9258PMID 22069321DOI 10.1074/JBC.M111.273730

Variant Set Distributions

ExAC Variants

Number Of Residues 40
Number Of SNVs 3
Number Of Permutations 64
Optimal Distance Threshold 5.0
K Statistic 0.333
p-value 0.346

Mapped Variants

[+] ExAC Missense Variants