3PHD.A | HDAC6

General Structure Information

PDB ID 3phd
HGNC Gene Label(s) HDAC6
Structure Name crystal structure of human hdac6 in complex with ubiquitin
Resolution 3.0Å
Reference AUTH H.OUYANG,Y.O.ALI,M.RAVICHANDRAN,A.DONG,W.QIU,F.MACKENZIE,AUTH 2 S.DHE-PAGANON,C.H.ARROWSMITH,R.G.ZHAITITL PROTEIN AGGREGATES ARE RECRUITED TO AGGRESOME BY HISTONETITL 2 DEACETYLASE 6 VIA UNANCHORED UBIQUITIN C TERMINI.REF J.BIOL.CHEM. V. 287 2317 2012REFN ISSN 0021-9258PMID 22069321DOI 10.1074/JBC.M111.273730

Variant Set Distributions

ExAC Variants

Number Of Residues 102
Number Of SNVs 13
Number Of Permutations 558
Optimal Distance Threshold 9.0
K Statistic 0.192
p-value 0.217

Mapped Variants

[+] ExAC Missense Variants