General Structure Information
| PDB ID | 3pfw |
| HGNC Gene Label(s) | GAPDHS |
| Structure Name | crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (gapds) complex with nad, a binary form |
| Resolution | 2.15Å |
| Reference | AUTH A.CHAIKUAD,N.SHAFQAT,R.AL-MOKHTAR,G.CAMERON,A.R.CLARKE,AUTH 2 R.L.BRADY,U.OPPERMANN,J.FRAYNE,W.W.YUETITL STRUCTURE AND KINETIC CHARACTERIZATION OF HUMANTITL 2 SPERM-SPECIFIC GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE,TITL 3 GAPDS.REF BIOCHEM.J. V. 435 401 2011REFN ISSN 0264-6021PMID 21269272DOI 10.1042/BJ20101442 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 334 |
| Number Of SNVs | 110 |
| Number Of Permutations | 19622 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.012 |
| p-value | 0.898 |
COSMIC
| Number Of Residues | 334 |
| Number Of SNVs | 5 |
| Number Of Permutations | 357 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.527 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 110 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.077 |
| p-value | 0.576 |