General Structure Information
| PDB ID | 3p1j |
| HGNC Gene Label(s) | GIMAP2 |
| Structure Name | crystal structure of human gtpase imap family member 2 in the nucleotide-free state |
| Resolution | 2.58Å |
| Reference | AUTH L.SHEN,W.TEMPEL,Y.TONG,X.GUAN,L.NEDYALKOVA,A.K.WERNIMONT,AUTH 2 F.MACKENZIE,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,D.W.ANDREWS,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN GTPASE IMAP FAMILY MEMBER 2 INTITL 2 THE NUCLEOTIDE-FREE STATEREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 193 |
| Number Of SNVs | 47 |
| Number Of Permutations | 4731 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.228 |
| p-value | 0.287 |
COSMIC
| Number Of Residues | 193 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.135 |
| p-value | 0.828 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
