General Structure Information
| PDB ID | 3p1a |
| HGNC Gene Label(s) | PKMYT1 |
| Structure Name | structure of human membrane-associated tyrosine- and threonine- specific cdc2-inhibitory kinase myt1 (pkmyt1) |
| Resolution | 1.7Å |
| Reference | AUTH A.CHAIKUAD,J.ESWARAN,O.FEDOROV,C.D.O.COOPER,T.KROELER,AUTH 2 M.VOLLMAR,T.KROJER,G.BERRIDGE,J.R.C.MUNIZ,A.C.W.PIKE,AUTH 3 F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,AUTH 4 S.KNAPPTITL STRUCTURE OF HUMAN MEMBRANE-ASSOCIATED TYROSINE- ANDTITL 2 THREONINE-SPECIFIC CDC2-INHIBITORY KINASE MYT1 (PKMYT1)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 81 |
| Number Of Permutations | 40451 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.019 |
| p-value | 0.135 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1135 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.267 |
| p-value | 0.641 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 81 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | -0.228 |
| p-value | 0.557 |